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- Homosexuality may be caused by chemical modifications to DNA
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Finally, I had the answers I wanted because I wrote them myself. In designing quizzes, I could elect myself the most well liked, brilliant, hilarious, hottest and most likely to succeed. Soon the power made me cynical. In the comments of my quizzes people would affirm their results as if they were scientifically proven: For years I had convinced myself that my failure to obtain a boyfriend was mathematical — too few parties attended, too few men befriended, too little time dedicated to Tinder.
I assumed there was a right way to do things and I had yet to master it. It was my good, second therapist who helped me realize that my nonexistent love life was not a quantitative issue but a qualitative one. Why did I imbue an amateurish, made-up, misspelled four-question quiz with more authority than I granted myself?
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Lost in the many hundreds of quizzes I had taken was the power of making my own choice. So I came out, tentatively. I joined OkCupid and answered the personality questions to the best of my ability. Finally in the right dating pool, I used my old friend, the quiz, as a life vest. When I saw someone I was drawn to, I did not study our compatibility, seeking out our mismatched traits. I just sent her a message. And when, after a back-and-forth, she asked me out, I said yes — not because I thought I should, or because doing so was the first step on the correct path forward.
Homosexuality may be caused by chemical modifications to DNA
I said yes because I wanted to. After several rounds of analysis—with the help of a specially developed machine-learning algorithm—the team identified five regions in the genome where the methylation pattern appears very closely linked to sexual orientation. One gene is important for nerve conduction, whereas another has been implicated in immune functions.
To test how important the five regions are, the team divided the discordant twin pairs into two groups. They looked at the associations between specific epi-marks and sexual orientation in one group, then tested how well those results could predict sexual orientation in the second group. Just why identical twins sometimes end up with different methylation patterns isn't clear. If Rice's hypothesis is right, their mothers' epi-marks might have been erased in one son, but not the other; or perhaps neither inherited any marks but one of them picked them up in the womb.
In an earlier review, Ngun and Vilain cited evidence that methylation may be determined by subtle differences in the environment each fetus experiences during gestation, such as their exact locations within the womb and how much of the maternal blood supply each receives. By Meredith Wadman Apr. By Jocelyn Kaiser Apr. All rights Reserved.